Publicaciones

• Le Guen Y, Luo G, Ambati A, et al. Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proc Natl Acad Sci U S A. 2023;120(36):e2302720120. doi:10.1073/pnas.2302720120
• García-González P, de Rojas I, Moreno-Grau S, et al. Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer's Disease Aetiopathogenesis in Men. Int J Mol Sci. 2023;24(2):898. Published 2023 Jan 4. doi:10.3390/ijms24020898
  
  

• Le Guen Y, Belloy ME, Grenier-Boley B, et al. Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurol. 2022;79(7):652-663. doi:10.1001/jamaneurol.2022.1166
  
  
• Bellenguez C, Küçükali F, Jansen IE, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet. 2022;54(4):412-436. doi:10.1038/s41588-022-01024-z
  
  
• de Rojas I, Hernández I, Montrreal L, Quintela I, Calero M, Royo JL, et al. Genomic Characterization of Host Factors Related to SARS-CoV-2 Infection in People with Dementia and Control Populations: The GR@ACE/DEGESCO Study. Journal of Personalized Medicine. 2021;11(12):1318.
  
  
• Moreno-Grau, S., Fernández, M.V., de Rojas, I. et al. Long runs of homozygosity are associated with Alzheimer’s disease. Transl Psychiatry 11, 142 (2021). https://doi.org/10.1038/s41398-020-01145-1
  
  
• de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B. Common variants in Alzheimer's disease: Novel association of six genetic variants with AD and risk stratification by polygenic risk scores. medRxiv. 2019 Nov 15(19012021).
  
  
• Sánchez-Juan P, Moreno S, de Rojas I, Hernández I, Valero S, Alegret M, Montrreal L, González PG, Lage C, López-García S, Rodrííguez-Rodríguez E. The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers. Frontiers in Aging Neuroscience. 2019;11.
  
  
• Moreno-Grau S, de Rojas I, Hernández I, Quintela I, Montrreal L, Alegret M, et al. Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimers and Dementia. 2019 Aug 13. pii: S1552-5260(19)35117-9. doi: 10.1016/j.jalz.2019.06.4950. PMID: 31473137.
  
  
• Van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, et al. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathologica. 2019.
  
  
• Dols-Icardo O, Iborra O, Valdivia J, Pastor P, Ruiz A, de Munain AL, et al. Assessing the role of TUBA4A gene in frontotemporal degeneration. Neurobiology of aging. 2016 Feb;38:215 e13-4. PubMed PMID: 26675813. Epub 2015/12/18.
  
  
• Dols-Icardo O, Nebot I, Gorostidi A, Ortega-Cubero S, Hernandez I, Rojas-Garcia R, et al. Analysis of the CHCHD10 gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain. Brain : a journal of neurology. 2015 Dec;138(Pt 12):e400. PubMed PMID: 26152333. Epub 2015/07/15.
  
  
• Pastor P, Moreno F, Clarimon J, Ruiz A, Combarros O, Calero M, et al. MAPT H1 Haplotype is Associated with Late-Onset Alzheimer's Disease Risk in APOEvarepsilon4 Noncarriers: Results from the Dementia Genetics Spanish Consortium. Journal of Alzheimer's disease : JAD. 2015;49(2):343-52. PubMed PMID: 26444794. Epub 2015/10/08.
  
  
• Ruiz A, Dols-Icardo O, Bullido MJ, Pastor P, Rodriguez-Rodriguez E, Lopez de Munain A, et al. Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia. Neurobiology of aging. 2014 Feb;35(2):444 e1-4. PubMed PMID: 24041969. Epub 2013/09/18.
  
  
• Thelen M, Razquin C, Hernandez I, Gorostidi A, Sanchez-Valle R, Ortega-Cubero S, et al. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiology of aging. 2014 Nov;35(11):2657 e13-9. PubMed PMID: 25042114. Epub 2014/07/22.
  
  
• Moreno-Grau S, de Rojas I, Hernández I, Quintela I, Montrreal L, Alegret M, et al. Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimers and Dementia. 2019 Aug 13. pii: S1552-5260(19)35117-9. doi: 10.1016/j.jalz.2019.06.4950. PMID: 31473137.